Thursday, November 21, 2024

What is difference between lubricant and glidant?


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Answer 1


Lubricants are substances added to granules (tablet granulation)  to help prevent adherence of the tablet material to the stainless steel processing equipment surfaces under compression forces. Thus, lubricants reduce or prevent adhesion of powder particles to tablet compression punch faces and dies or to the rolls of a roller compactor. They promote flow, reduce interparticle friction, and facilitate the smooth ejection of compressed tablets from the die cavity. 

Glidants are added to tablet formulation to enhance the flow properties of powders in the hopper and the feed frame into the die in the tablet press. Glidants act in between the particle and the surface of the hopper or dies to reduce friction and aid in enhanced flow.

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