Pharmacokinetics involves the study of drug absorption, distribution, metabolism, and excretion.

Key principles include:

Absorption: How drugs enter the bloodstream.

Distribution: How drugs spread within the body’s tissues.

Metabolism: The transformation of drugs by the body.

Excretion: Elimination of drugs from the body, often through the kidneys.

These principles impact dosing as they determine the drug’s concentration over time. Factors like patient age, organ function, and drug interactions influence how medications are prescribed and adjusted to achieve therapeutic effects while minimizing side effects or toxicity. Individualized dosing considers these pharmacokinetic factors for optimal clinical outcomes.