Thursday, November 7, 2024

Pharmaceutical Technology

In-Process Quality Control (IPQC) of Pharmaceutical Dosage Forms

In-process quality control tests are simply routine checks that are performed during production. They are those tests carried out before manufacturing process is completed to…
Quality Control Requirements for Pharmaceutical Dosage Forms

Quality Control Requirements for Pharmaceutical Dosage Forms

Quality control of pharmaceutical formulations is an essential operation in the production of drugs. It is a procedure or set of procedures designed to ensure…
Quality Control Requirements for Pharmaceutical Dosage Forms
Direct compression excipients

Direct Compression Excipients: Properties and Uses

This article outlines the various direct compressible excipients that have been used in the manufacture of tablets by direct compression method, with particular emphasis on what is expected from such excipients in terms of their functionality. A comprehensive understanding of the behaviour of these materials is essential to avoid potential problems during manufacturing as there is no chance to cover up flaws in raw materials in direct compression as there is in wet granulation process.

Direct compression excipients
Direct Compression Technoogy: Manufacture of Tablets by Direct Compression Method

Manufacture of Tablets by Direct Compression Method

The processing of drug with excipients can be achieved without any need of granulation and related unit operations. By simply mixing in a blender, formulation…
Direct Compression Technoogy: Manufacture of Tablets by Direct Compression Method
Recent Advances in Granulation Technology for Pharmaceutical Formulations

Recent Advances in Granulation Technology for Pharmaceutical Formulations

Granulation is an important unit operation in which fine powder particles are made to adhere to form larger agglomerates called granules. The process is designed…
Recent Advances in Granulation Technology for Pharmaceutical Formulations
Dry Granulation: Manufacture of Tablets by Dry granulation method

Manufacture of Tablets by Dry granulation method

Dry granulation also referred to as precompression or double compression is a size enlargement process designed to improve the flow and compression characteristics of powders…
Dry Granulation: Manufacture of Tablets by Dry granulation method
Featured image for advantages and disadvantages of wet granulation

Advantages and Disadvantages of Wet Granulation

Wet granulation is the process of size enlargement in which a liquid is added to a powder with agitation to produce agglomeration or granules. It…
Featured image for advantages and disadvantages of wet granulation

Tablet Manufacture by Wet Granulation Method

Granulation is a unit operation in which small powder particles are gathered together to form agglomerates called granules. To achieve cohesion between the powders, it…
Manufacture of pharmaceutical tablets

Manufacture of Pharmaceutical Tablets

The design and manufacture of pharmaceutical tablets is a complex multi-stage process whereby formulation scientists ensure that the correct amount of drug substance in the…
Manufacture of pharmaceutical tablets
featured image: Excipients Used In the Manufacture of Tablets

Excipients Used In the Manufacture of Tablets

Drug products usually contain inactive, non-medicinal substances other than the therapeutic agent(s). These substances are called excipients, and they are intentionally included in a drug…
featured image: Excipients Used In the Manufacture of Tablets
Featured image of solid dosage form: tablets

Solid Dosage Forms: Tablets

Tablets are solid dose pharmaceutical preparation containing drug substances usually prepared with the aid of suitable pharmaceutical excipients. They may vary in size, shape, weight,…
Featured image of solid dosage form: tablets

Understanding Pharmaceutical Dosage Forms

Dosage forms are believed to be as old as man himself, though doubts about the “measures” used by early man in quantifying these formulations never…
pharmaceutical applications of native starch

Pharmaceutical Applications of Native Starch

Starch is a naturally occurring polysaccharide polymeric material that is widely present in cytoplasm of the plant cells found in fruit, root, pedicle, and leaves…
pharmaceutical applications of native starch
Pictures of Plastic Packaging Systems used in Pharmaceutical industries

Plastic Containers for Pharmaceutical Use

Plastic packaging systems define a set of packaging materials that are composed wholly or in substantial portion of plastic materials which contain or is intended…
Pictures of Plastic Packaging Systems used in Pharmaceutical industries
Drug-excipient compatibility studies

Preformulation Studies: Drug-Excipient Compatibility Studies

Drug-excipient compatibility studies represent an important phase in drug development. Before a drug substance is formulated into the desired dosage form, there is need for…
Drug-excipient compatibility studies
Stability Analysis-Stability Chamber

Preformulation Studies: Stability analysis

Stability analysis is an area of great interest in preformulation studies. It is a complex set of procedures performed on candidate drug molecules or dosage…
Stability Analysis-Stability Chamber
solubility analysis

Preformulation Studies: Solubility analysis

Solubility is an essential and extensively studied preformulation parameter. It focuses on drug-solvent system that could occur during drug delivery. Such information is important to…
solubility analysis
Bulk characterization

Preformulation Studies: Bulk Characterization

The development of an efficient dosage form usually starts with preformulation studies. These studies are designed to investigate and deliver all necessary data useful to…
Bulk characterization
Preformulation studies

Preformulation Studies: A Foundation for Dosage Form Development

The development of an efficient dosage form is usually a long and complex process that involves a lot of capital and teamwork from different disciplines.…
Preformulation studies
Glass Containers

Glass Containers for Pharmaceutical Use

Glass containers are among the primary packaging material that has found use in the pharmaceutical industries.  A large number of pharmaceutical formulations have been packaged using…
Glass Containers
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